Issue link: https://www.e-digitaleditions.com/i/1491587
Inhalation February 2023 19 distal lung epithelial barrier. Mol Pharm, 2014. 11(3): p. 995-1006. 44. Jensen, C., et al., Is it time to start transitioning from 2D to 3D cell culture? Front Mol Biosci, 2020. 7: p. 33. 45. Langhans, S.A., ree-dimensional in vitro cell culture models in drug discovery and drug reposi- tioning. Front Pharmacol, 2018. 9: p. 6. 46. Miller, A.J., et al., In vitro models to study human lung development, disease and homeostasis. Physiol- ogy (Bethesda), 2017. 32(3): p. 246-260. 47. Grainger, C.I., et al., Culture of Calu-3 cells at the air interface provides a representative model of the airway epithelial barrier. Pharm Res, 2006. 23(7): p. 1482-1490. 48. Haghi, M., et al., Time- and passage-depen- dent characteristics of a Calu-3 respiratory epithe- lial cell model. Drug Dev Ind Pharm, 2010. 36(10): p. 1207-1214. 49. Ren, H., et al., An optimised human cell culture model for alveolar epithelial transport. PloS One, 2016. 11(10): p. e0165225. 50. Bai, S., et al., Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies. J Pharm Sci, 2008. 97(3): p. 1165-1178. metalloproteinase activity. J Mol Med (Berlin), 2014. 92(6): p. 615-628. 37. Shiratori, B., et al., Quinolone-induced upreg- ulation of osteopontin gene promoter activity in human lung epithelial cell line A549. Antimicrob Agents Chemother, 2012. 56(6): p. 2868-2872. 38. Puerta, A., et al., Early pharmacological profiling of antiproliferative compounds by live cell imaging. Molecules, 2022. 27(16) p. 5261. 39. Harikrishnan, K., et al., Cell derived matrix fibulin- 1 associates with epidermal growth factor receptor to inhibit its activation, localization and function in lung cancer Calu-1 cells. Front Cell Dev Biol, 2020. 8: p. 522. 40. Almazi, J.G., et al., Protective abilities of an inhaled DPI formulation based on sodium hyal- uronate against environmental hazards targeting the upper respiratory tract. Pharmaceutics, 2022. 14(7): p. 1323. 41. Ong, H.X., et al., Pharmaceutical applications of the Calu-3 lung epithelia cell line. Expert Opin Drug Deliv, 2013. 10(9): p. 1287-1302. 42. Sakagami, M., In vitro, ex vivo and in vivo meth- ods of lung absorption for inhaled drugs. Adv Drug Deliv Rev, 2020. 161-162: p. 63-74. 43. Salomon, J.J., et al., e cell line NCl-H441 is a useful in vitro model for transport studies of human