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© 2014 Capsugel Belgium NV All rights reserved. Some HPMC capsules are formulated with secondary gelling agents and ionic gel promoters – which may slow down release of active ingredients. Capsugel's Vcaps ® Plus HPMC capsules are made through a proprietary manufacturing process that eliminates the need for gelling systems. They disintegrate and release their contents independent of pH and ionic strength of the test media. To discover how Vcaps ® Plus capsules can optimize performance, improve product stability, and reduce both variability and timelines in your drug development, download our free whitepaper. VcapsPlus.com 888-783-6361 v o n n f i s o r a e y w s e g n n i v e i h c A s t s i i h . T D & e R v i t a v o f r e n p s i d r a d n a t w s . t l u s e e r h s t s e k a e t c n a m r o o n f o i t a r g e t n i s i n d i n y a r e v i l e d d e z i m i t p r o o e c n a m r o f r e d p n e m i d t n y a t i l i b a i r a v o . To a i d e t m s e e t h t d f e e e n h s t e t a n i m i l e n e i d e r g n e i v i t c f a o s p a C c M P e H m o S t n e m p o l e v e g d u r r d u o n y s i e n i l e p a s c u l P ® s p a c w V o r h e v o c s i o d i s i y d e . Th s m e t s y g s n i l l e r g o d f s H u l P ® s p a c s V ' l e g u s p a . C s t n n o c e h s t i d w e t a l u m r o e f r s a e l u o n f o i t a r g e t n i s i n d i e p pa e t i h e w e r r f u d o a o l n w o , d t c n a m r o f r e e p z i m i t p n o a s c e l u s p t n o r c i e h e t s a e l e d r n e a t a r g e t n i u o r h e t d a e m r s a e l u s p a C c M P c g i n o d i n s a t n e g g a n i l l e y g r a d n n y a r e v i l e d d e z i m i t p r o o r n , a y t i l i b a t t s c u d o r e p v o r p m , i e c o d i n H a f p t o n e d n e p e d n s i t n e t n i r u t c a f u n a y m r a t e i r p o r h a p g u w d o l y s a h m c i h s – w r e t o m o r l p e c g . e c n a m r o f r e d p n h t o e b c u d e d r n f h o t g n e r t c s i n o t a h s t s e c o r g p n e s a e l e n r w o w d com s. u l P s p a c V e m i d t n y a t i l i b a i r a v © 2014 Capsugel Belgium NV All rights reserved. 1 6 3 6 - 3 8 7 -7 8 8 8 t n e m p o l e v e g d u r r d u o n y s i e n i l e © 2014 Capsugel Belgium NV All rights reserved. e p pa e t i h e w e r r f u d o a o l n w o , d t . r b-TOCFN_1-7_Masters 5/14/14 10:12 AM Page 5