Issue link: https://www.e-digitaleditions.com/i/1331851
8 January/February 2021 Tablets & Capsules Pete DeLuca Qualicaps Troubleshooting capsule filling operations capsule filling T This article describes common problems encountered during capsule filling and provides troubleshooting tips for solving them. wo-piece hard-shell capsules are an attractive and ver- satile solid oral dosage delivery system that can be used with powder, granule, minitablet, liquid, and semi-solid formulations. Modern hard capsules are designed to work with fully automated capsule filling machines at fill rates of 200,000 or more capsules per hour. Achieving max- imum speed, efficiency, and throughput during capsule filling requires care and planning, from the receipt of the empty capsules to final packaging.