Issue link: https://www.e-digitaleditions.com/i/807837
Povidone excipient Vivapharm PVP (povidone) for use in wet granulations enhances bioavail- ability and dissolution of poorly solu- ble APIs. Excipient balances high binding capacity with adhesive strength—even at concentrations of 2 to 5 percent—and its low-viscosity grade ensures easy handling. Readily soluble in water and variety of organic solvents, excipient provides process- ing flexibility. Free-flowing powder has spherical particles for rapid dis- persibility, and its non-ionic polymers prevent negative interactions with ionic APIs. Company also offers Vivapharm PVPP (crospovidone) and PVP/VA 64 (copovidone). JRS Pharma, Patterson, NY. Tel. 845 878 3414 www.jrspharma.com industry innovations Benchtop liquid capsule filler RoboLQ capsule filler doses as little as 1 microliter of liquid into capsules using fixed or variable-volume dispensing. Applications include R&D, compounding, and clinical trial materials. Company offers three models that fill capsule sizes 00 to 5. Lab model doses as many as eight capsules at once and as many as 2,500 per hour. Blend model uses peristaltic pump to channel liquid through reservoir that main- tains fluid at even level to ensure actives and excipients combine into homogeneous fill. Thermal model applies gentle, even heat to ultra-thick materials to promote flow and prevent obstructions. Machine fills capsules with as much as 1,000 micro- liters of liquid. All models handle minimum batch size of 16 capsules. Formulation software factors in capsule size, desired dosage, and active ingredient's purity to help determine amounts of active and inactive to include. Built-in validation mech- anism prevents overfills. CapsCanada, Pompano Beach, FL. Tel. 954 979 6440 www.capscanada.com Anti-stick coating I Holland PharmaCote ECxtra coating for tablet punches eliminates pores and micro-cracks common to hard chromium coatings, improving resistance to corrosion, wear, and sticking. It also results in stronger punch because there is no hydrogen embrittlement of substrate. Coating is 2 to 4 microns thick and provides punch with hardness of 1700 on Vickers scale. Coated punches are easy to clean in ultrasonic bath followed by polishing. IPR, Bartlett, IL. Tel. 630 823 4700 www.tablettingscience.com Tablets & Capsules April 2017 51