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T Tablets & Capsules July 2017 11 formulation An introduction to self-emulsifying nutraceutical delivery systems (SENDS) John K. Tillotson Abitec Like their counterparts in the pharmaceutical industry, many dietary ingredients are poorly soluble. This article describes how self-emul- sifying nutraceutical delivery systems improve solubility and enable formulators to deliver these difficult ingredients in solid dosage form. he nutraceutical benefits of medium-chain triglycerides (MCTs) are well known. The primary benefit: MCTs are quickly converted in the liver to energy-providing ketone bodies like beta-hydroxy butyrate and acetoacetate. These ketone bodies can be employed as energy substitutes for glucose. For that reason, MCTs have been widely studied and are employed as a dietary treatment for numerous dis- ease states, including epilepsy, Alzheimer's disease, Parkinson's disease, ischemia brain injury, and diabetes [1, 2]. Other research has documented the benefits of a keto- genic diet supplemented with MCT in weight loss, athlet- ics, and energy and replenishment [3].