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6 January 2019 Tablets & Capsules solution time. The resulting data strongly suggested that the capsule coatings delayed API release. markets Packaging machinery market to reach $42.2 billion by 2021 RESTON, VA—The global pack- aging machinery market is projected to reach $42.2 billion by 2021, a c o m p o u n d a n n u a l g r o w t h r a t e (CAGR) of 2.8 percent, according to a report by PMMI. Factors driving growth include population increase, a thriving middle class, heightened sustainability concerns, increased spending power in developing regions, increased popularity of flex- ible packaging, a growing demand for smart packaging, and serializa- tion. The pharmaceutical packaging sector is expected to experience the fastest growth, at 4.1 percent CAGR for the forecast period (2016 to 2021). Horizontal form, fill, and seal machinery is forecast to be the fast- est growing machine group, with a CAGR of 3.2 percent. Gelatin capsules dominate empty-capsule market N O R T H B R O O K , I L — T h e global empty-capsule market will grow at a CAGR of 7.4 percent and will be worth $2.79 billion in 2023, according to a report by Markets- andMarkets. Factors driving growth include an increased use of capsule formulations among the growing geriatric population, increasing R&D activities and clinical trials, growth of the pharmaceutical market, and advancements in capsule-delivery technologies. Key market players include Capsugel, ACG Worldwide, Qualicaps, Suheung, CapsCanada, Qingdao Yiqing Medicinal Cap- sules, Shanxi Guangsheng Medicinal Capsules, Healthcaps India, Snail Pharma Industry, Roxlor, Sunil Healthcare, Medi-Caps, Nectar Lifesciences, Natural Capsules, and Bright Pharma Caps. acetaminophen products across five companies by measuring dissolution every two minutes during 30-minute intervals. When the researchers com- pared the 600 immediate-release tab- lets to the 600 gelatin capsules mar- keted as rapid- or fast-release, they found that the gelatin capsules took 37 seconds longer to dissolve than the tablets. In follow-up studies, the researchers removed the blue and red coatings from the rapid-release gela- tin capsules before measuring the dis- research Rapid-release acetaminophen gelatin capsules dissolve slower than tablets, study finds NEW HAVEN, CT—On average, rapid-release acetaminophen gelatin capsules dissolved slower than com- pany-matched immediate-release tablets, according to a study by Valisure, an online analytical phar- macy. The study analyzed 1,200