Tablets & Capsules September 2019 35
6. Ulrich Laufs, Volker Rettig-Ewen, and Michael
Böhm. "Strategies to improve drug adherence." European
Heart Journal. Vol. 32, No. 3, pages 264-268.
7. Justin Kalafat and Fernando Diez. "Hard Shell Cap-
sules: An Appropriate Choice for Liquid Formulations."
AAPS 2018.
8. Rudi Wajda, Jürgen Zirkel, and Tanja Schaffer.
"Increase of Bioavailability of Coenzyme Q
10
and Vita-
min E." Journal of Medicinal Food. Vol. 10, No. 4, pages
731-734.
Justin Kalafat is scientific business development manager for
ACG (www.acg-world.com). The company offers end-to-end
capsule and tablet manufacturing solutions for the pharmaceu-
tical industry.
contained within a capsule. The most important develop-
ment for these applications would be working toward a
release profile that is beneficial for both the product and
consumers. With the available technology and acceptance
of novel products in the pharmaceutical and nutraceutical
markets, the only obstacles limiting new product develop-
ment lie in the minds of formulation scientists. T&C
References
1. Tschanter (Pharm. Zeit.). Pharmaceutical Journal. April
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2. L. Z. Benet. "Predicting Drug Disposition by Appli-
cation of BDDCS." AAPS 2018.
3. Jnanadeva Bhat, Fernando Diez, and Justin Kalafat.
"Liquid-Filled Hard Capsules Help Meet Today's Formu-
lation Challenges." Tablets & Capsules. September 2017,
pages 39-43.
4. US Food & Drug Administration. "Finding and
Learning about Side Effects (adverse reactions)." July 19,
2018. https://www.fda.gov/drugs/drug-information-
consumers/finding-and-learning-about-side-effects-
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5. Fernando Diez, Justin Kalafat, and Jnanadeva Bhat.
"Fixed Dose Combinations in Capsules." Contract Pharma.
March 2019, pages 56-59.
