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Co-processed lactose CombiLac co-processed excipient for use in direct-compression formulations contains 70 percent alpha-lactose monohydrate, 20 percent microcrys- talline cellulose, and 10 percent white corn starch. Components are integrated into cohesive monoparticles that improve compaction properties and flow performance compared to equiva- lent admixture of its ingredients. Excip- ient simplifies development and manu- facture and provides rapid, hardness-independent tablet disintegra- tion while minimizing tablet friability. Product complies with USP, Ph.Eur., and JP requirements. Meggle USA, White Plains, NY. Tel. 914 682 6891 www.meggle-pharma.com 20 July 2015 Tablets & Capsules Ultrafine HPC HPC-SSL Superfine Powder (SFP) hydroxypropyl cellulose (HPC) has lowest molecular weight and finest par- ticles (20 microns), improving its per- formance over other HPCs. Addition of 1 percent SSL-SFP to problem formula- tions can resolve tablet capping and hardness problems; tablet size can be reduced by replacing 15 percent MCC with 3 percent SSL-SFP. Super-low-vis- cosity grade (2 to 2.9 megapascal-sec- onds at 20°C in 2 percent aqueous solu- tion) promotes high compressibility in dry-binding applications and allows rapid disintegration and dissolution. Compared to common dry binders, excipient produces harder tablets and lower friability without hindering API release. HPC can be used with direct- compression immediate-release tablets, orally disintegrating tablets, roller-com- pacted/dry granulations, HPMC matrix tablets (hardness enhancement), and poorly compressible APIs. Nisso America, New York, NY. Tel. 212 490 0350 www.nissoexcipients.com Inorganic salts Company's high-purity inorganic salts include ascorbates, carbonates, citrates, fumarates, gluconates, lactates, malates, nitrates, phosphates, succinates, and sulfates. Company offers products with ultra-low heavy metal content and Jostcote microen- capsulated mineral salts that help mask taste and odor of APIs and minimize inter- action of components. Manufactured at its 210,000-square-foot, FDA-registered site, products meet bulk pharmaceutical cGMP and US and EU pharmacopeial stan- dards; all are free of allergens and BSE/TSE pathogens. Validated processes ensure consistent lots that meet regulatory requirements. Jost Chemical, St. Louis, MO. Tel. 314 428 4300 www.jostchemical.com Need info? New subscriber? Find past articles at www.tabletscapsules.com. Click on Article index Excipients Company's excipients include Microcel microcrystalline cellulose (MCC), Solutab croscarmellose sodium, Exposol sodium starch glycolate, Tabdone crospovidone, Sorb-Cel effervescent base, and Tablulose SC colloidal MCC. In-process monitoring and control ensure compliance with all compendia. Production facilities are GMP-certified. Company also manufactures and pack- ages pharmaceuticals. Blanver, Boca Raton, FL. Tel. 561 416 5513 www.blanver.com