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This flexibility in solids concentrations allows manufac- turers to optimize the coating system to suit a range of processes, from traditional batch pan coaters to high- throughput continuous coaters. T&C Acknowledgements The authors thank Rainer Bastian and Rolf Eckel of Driam for their expertise in conducting the trials. We also thank Chris Neely and Joseph Quinn of Colorcon for their careful preparation of the marked tablets and for analyzing the coated tablet samples. References 1. Cunningham CR, Hansell J, Nuneviller III F, Rajabi- Siahboomi AR (2010). Evaluation of recent advances in continuous film coating processes. Drug Dev Ind Pharm (36) 2:227-233. 2. Mancoff WO (1998). Film coating compressed tablets in a continuous process. Pharm Technol 22 (Oct): 12-18. 3. Suzzi D, Toschkoff G, Radl S, Machold D, Fraser S, Glasser B, Khinast J (2012). DEM simulation of continuous tablet coating: effect of tablet shape and fill level on inter- tablet coating variability. Chem Eng Sci 69 (2012) 107-121 4. Porter S, (2010). The role of high-solids coating sys- tems in reducing process costs. Tablets & Capsules (8) 3: 10-16. 5. Neely C, Cunningham C, Rajabi-Siahboomi AR (2015). Evaluation of film coating weight uniformity, tablet progression and tablet transit times in a high throughput continuous coating process. Poster presentation, AAPS 50th Annual Arden Conference, Baltimore, MD. 6. Teckoe J, Mascaro T, Farrell T and Rajabi-Siahboomi AR (2013). Process optimization of a novel immediate release film coating system using QbD principles. AAPS PharmSciTech (14) 2: 531-540. Charles Cunningham is senior manager of product development at Colorcon, 275 Ruth Road, Harleysville, PA. Tel. 215 256 7700. Website: www.colorcon.com. Jörg Crönlein is senior area technical manager at Colorcon, Buchwiese 18, 65510 Idstein, Germany. Oliver Nohynek is managing director of Driam, Aspenweg 19-21, 88097 Eriskirch, Germany. Tel. +49 75 41 97 030. Driam's US office is in Spartanburg, SC. Website: www.driam.com. Table 2 Variability in weights of coated tablets: Continuous versus batch Solids concentration of coating dispersion (%) Coating weight variability (% RSD) in Driaconti-T Pharma at 3% WG Coating weight variability (% RSD) in traditional 48- inch batch pan at 20.0 14.1 18.7 25.0 15.2 23.9 30.0 15.7 n/a 35.0 17.2 n/a Appearance of tablets coated at 35 percent solids concentration Figure 8 Gloss and surface roughness of coated tablets Coated tablet surface roughness (Sa) (n=4) Coated tablet gloss (GU) Coating solids concentration 20% 25% 30% 35% 120 110 100 90 80 70 60 50 7.0 6.5 6.0 5.5 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0 0.5 0.0 Gloss Surface roughness 26 October 2015 Tablets & Capsules TABLETS & CAPSULES BOOKSTORE Go to www.tabletscapsules.com and click on "Bookstore."