Issue link: https://www.e-digitaleditions.com/i/701238
Tablets & Capsules July 2016 27 7+20$6(1*,1((5,1*,1&:HVW&HQWUDO5G +RIIPDQ(VWDWHV,/7(/ :::7+20$6(1*&20 7+20$67$%/(7 35(66722/,1* Functionalized calcium carbonate Omyapharm functionalized calcium carbonate (FCC) for orally dispersible granules (ODGs) and orally dispersible tablets (ODTs) offers fast disintegration time and high API loading capacity. Excipient allows you to directly com- press ODGs into tablets that disinte- grate in less than 10 seconds. During dry granulation or tabletting, FCC's lamellar surface structure interlocks to provide large number of contact points, resulting in greater mechanical strength at lower compression pressures than other excipients. This preserves poros- ity of granules and tablets and enables them to take up water faster for faster disintegration. ODGs can be produced without binders via roller compaction. Omya Life Sciences, Long Beach, CA. Tel. 562 961 3333 www.omya.com Direct-compression lactose Sheffield DTHV anhydrous lactose for direct compression of moisture-sensi- tive APIs has fewer fines than other anhydrous lactoses and improves flowa- bility and tablet weight uniformity while maintaining tablet hardness at low compaction pressures. Other ben- efits include low friability, good disso- lution, 48-month moisture stability, and minimal color development. It meets requirements of major international pharmacopeias. All ingredients are cer- tified rennet free. Company also offers LurbiTose self-lubricating co-processed excipients available in anhydrous lac- tose, spray dried lactose, MCC, or man- nitol. Kerry, Beloit, WI. Tel. 608 363 1200 www.sheffieldbioscience.com