Issue link: https://www.e-digitaleditions.com/i/1267517
18 July 2020 Tablets & Capsules Issue focus excipients & formulation Bioavailability enhancing excipients Company develops and manufactures lipid-based excipients to enhance the bio- availability of poorly water-soluble and poorly permeable pharmaceutical APIs. Offerings include Capmul bioavailability enhancer excipients, which are medium- chain mono- and diglycerides and propylene glycol esters. Functional lipid excip- ients are a suitable starting point for formulating BCS Class II and IV (poorly water-soluble) and BCS Class III and IV (poorly permeable) molecules. Company's lipid excipients can also be used to aid solubilization, permeability, sustained/mod- ified release, and processing, and are widely used to formulate self-emulsifying drug delivery systems (SEDDs). Abitec, Columbus, OH 614 429 6464 www.abiteccorp.com Filler-binder galenIQ 721 isomalt filler-binder can help pharmaceutical and nutraceutical man- ufacturers overcome formulation difficulties when using sticky and oily plant extracts in solid dosage forms. Excipient absorbs oily plant extracts, leaving a dry flowable powder, which helps retain the mixture's homogeneity and simplifies the production of robust tablets with high content uniformity. Filler-binder is water-soluble, allowing plant-extract-based tablets to disintegrate rapidly without the use of a super-disintegrant or additional binders. Excipient is suitable for a broad range of tablet products, from chewables to orally disintegrating mini- tablets. Company's galenIQ products are available in different grades to serve a broad range of solid dosage manufacturing needs. Excipients have a sucrose-like mouthfeel and flavor that reduces unpleasant tastes and enhances palatability, promoting patient compliance. Beneo, Parsippany, NJ 973 867 2140 www.galeniq.com DPI lactose excipients InhaLac 140 and 150 milled lactose monohydrates for dry powder inhalation (DPI) applications complement the company's coarser-milled carrier lactose excip- ient grades. Excipients' particle size distribution is characterized by the typical flow and surface characteristics of milled lactose grades. Both lactose products have highly controlled and homogeneous powder characteristics, high microbial quality and low endotoxins, and high stability for extended shelf life that only requires retest after 24 months. Meggle, Pawling, NY 845 289 0264 www.meggle-pharma.com