Issue link: https://www.e-digitaleditions.com/i/1138630
24 July 2019 Tablets & Capsules A significant part of the global population—particularly geriatric, pediatric, and psychiatric patients—has diffi- culty swallowing solid oral dosage forms (SODFs). Approximately 40 to 60 percent of adults living in assist- ed-living facilities and nursing homes are reported to have trouble swallowing [1,2]. And each year, approxi- mately 569,000 children, ages three to seven, also have difficulty swallowing [3]. Others who suffer from drug-induced dysphagia or deglutition disorders face sim- ilar difficulties. When developing a new drug product, it is imperative to formulate inclusive, patient-friendly options to enable compliance. Orally disintegrating tablets (ODTs) are rising in popularity because of their ease of administration and improved patient com- pliance, creating the need for excipients that enable both taste masking and rapid disintegration. This article describes a method for taste masking ODT formulations by coating the active phar- maceutical ingredient (API) with an aqueous ethylcellulose polymer dispersion combined with different plasticizers. Taste masking orally disintegrating tablet formulations Sreeramaiah Arunkumar, Vinay Muley, Michael Baumann, and Rina Chokshi DuPont Nutrition & Biosciences orally disintegrating tablets